Leukemia Stem Cells in Hematologic Malignancies: Advances in Experimental and Clinical Research

Leukemia stem cells (LSCs) are a rare population of cells that are responsible for the initiation and maintenance of leukemia. LSCs are resistant to conventional chemotherapy and radiation therapy, and they can give rise to new leukemia cells after treatment. Therefore, targeting LSCs is a promising strategy for the treatment of leukemia.

Leukemia Stem Cells in Hematologic Malignancies (Advances in Experimental Medicine and Biology Book 1143)

by Michael Sparrow

4.1 out of 5

Language	:	English
File size	:	19249 KB
Text-to-Speech	:	Enabled
Enhanced typesetting	:	Enabled
Print length	:	394 pages
Screen Reader	:	Supported

FREE

This book provides a comprehensive overview of the latest advances in experimental and clinical research on LSCs. The book is divided into three sections:

1. Section 1: Biology of LSCs
2. Section 2: Experimental Therapeutics Targeting LSCs
3. Section 3: Clinical Trials Targeting LSCs

Section 1: Biology of LSCs

The first section of the book provides a detailed overview of the biology of LSCs. This section covers the following topics:

• The identification and characterization of LSCs
• The role of LSCs in the development and progression of leukemia
• The mechanisms of LSC resistance to therapy

Section 2: Experimental Therapeutics Targeting LSCs

The second section of the book reviews the latest advances in experimental therapeutics targeting LSCs. This section covers the following topics:

• The development of new drugs and drug combinations that target LSCs
• The use of gene therapy and immunotherapy to target LSCs
• The preclinical evaluation of LSC-targeting therapies

Section 3: Clinical Trials Targeting LSCs

The third section of the book discusses the latest clinical trials targeting LSCs. This section covers the following topics:

• The design and conduct of clinical trials targeting LSCs
• The results of early-phase clinical trials targeting LSCs
• The future directions of clinical research on LSCs

This book provides a comprehensive overview of the latest advances in experimental and clinical research on LSCs. The book is a valuable resource for researchers, clinicians, and students who are interested in the field of leukemia stem cell biology.

Leukemia Stem Cells in Hematologic Malignancies (Advances in Experimental Medicine and Biology Book 1143)

by Michael Sparrow

4.1 out of 5

Language	:	English
File size	:	19249 KB
Text-to-Speech	:	Enabled
Enhanced typesetting	:	Enabled
Print length	:	394 pages
Screen Reader	:	Supported

FREE